DIABETES MELLITUS DENGAN HIPERTENSI MENINGKATKAN RISIKO CHRONIC KIDNEY DISEASE: STUDI KASUS KONTROL DI RS PANTI NIRMALA MALANG

Rea Ariyanti, Cecilia Wdijati Imam

Abstract


Chronic Kidney Disease (CKD) is a global public health problem with the prevalence and incidence of increased renal failure. Approximately 1 in 10 global populations suffers from chronic renal failure at a particular stage. There are several risk factors that are suspected to increase the incidence of Chronic Kidney Disease, one of which is Diabetes Mellitus. This study aims to determine the relationship between diabetes mellitus and chronic kidney disease in the Panti Nirmala Hospital. Research design is case-control. The sample amounted to 286 respondents, consisting of 143 case groups and 143 control groups. Data analysis using logistic regression analysis. The results of multivariable analyses showed that there are two confounding variables in the relationship of diabetes mellitus with CKD i.e. gender and age. In addition, diabetes mellitus also interacts with hypertension. Diabetes mellitus interacts with hypertension to increase the risk of CKD (OR=15.9; 95% CI 4.4 to 57.4; p=<0.001). After controlled by gender and age, Hypertension or a history of Hypertension, respondents with Diabetes Mellitus were 15.9 times more likely to have Chronic Kidney Disease than non-Diabetes Mellitus respondents. 

Keywords


Chronic Kidney Disease; Diabetes Mellitus; Hypertension.

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References


Kementerian Kesehatan RI. (2019). Hasil Utama RISKESDAS 2018. Badan Penelitan dan Pengembamngan Kesehatan: Jakarta 2.

Kementerian Kesehatan RI. (2017). Situasi Penyakit Ginjal Korinis. Pusat Data dan Informasi Kementerian Kesehatan RI: Jakarta

Hill, N., L Oke, J., A. Hirst, J., O’ Callaghan, C. A. Lasserson, D., Richard Hobbs, F., et al. 2016 Global Prevalence Of Chronic Kidney Disease – A Systemic Review and Meta-Analysis.

Delima, Tjitra E, Tana L, Halim FS, Ghani L, Siswoyo H, et al. Risk Factors for Chronic Kidney Disease: A Case Control Study in Four Hospitals in Jakarta in 2014. Buletin Penelitian Kesehatan. 2017 Mar; Vol 45, No.1:17-26.

Stojceva TO., Eftimovska ON., Taneva B. 2016. Prevalence of Diabetes Mellitus in Patients with Chronic Kidney Disease. Macedonian Journal of Medical Science. Vol 4(1): 79-82. https://dx.doi.org/10.3889/oamjms.2016.019

Hahr, A. J., & Molitch, M. E. 2015. Management of diabetes mellitus in patients with chronic kidney disease. Clinical diabetes and endocrinology, 1, 2. https://doi.org/10.1186/s40842-015-0001-9

Rivandi, J & Yonata, A 2015. ‘Hubungan Diabetes Melitus Dengan Kejadian Gagal Ginjal Kronik’, Majority Volume 4 Nomor 9 Desember 2015, diakses 17 Oktober 2018, http://juke.kedokteran.unila.ac.id/index.php/majority/article/view/1404

Kazancioglu, Rumyza. 2013. Risk Factors for Chronic Kidney Disease: an Update. Kideny International Supplements. 3: 368-371. https://doi.org/10.1038/KISUP.2013.79

Philip McFarlane., David Cherney., Richard E. Gilbert., et al. 2018. Chronic Kidney Disease in Canada. Canadian Journal of Diabetes. https://doi.org/10.1016/j.jcjd.2017.11.004

Radica Z. Alicic., Michele T. Rooney., Katherine R. Tuttle. 2017. Diabetic Kidney Disease: Challenges, Progress, and Possibilities. Clin J Am Soc Nephrol. Vol 12: 2032–2045. https://doi.org/10.2215/CJN.11491116

Yi Chin Lin., Yu Hsing Chang., Shao Yu Yang., et al. 2017. Update of Pathophysiology and Management of Diabetic Kidney Disease. Journal of the Formosan Medical Association. Vol 117; 662-675. https://doi.org/10.1016/j/jfma.2018.02.007.

Elaine KU., Benjamin JL., Jenny Wei., Matthew RW (2019). Hypertension in CKD: Core Curriculum. 2019. American Journal Kidney Disease. Vol 74(1): 120-131. https://doi:10.1053/j.ajkd.2018.12.044

Fanelli C., Delle H., Cavaglieri RC., Dominguez WV., Noronha IL. 2017. Gender Differences in the Progression of Experimental Chronic Kidney Disease Induced by Chronic Nitric Oxide Inhibition. Biomed Research International. Vol 2017. https://doi.org/10.1155/2017/2159739

Center for Disease and Control Prevention (CDC). 2019. Chronic Kidney Disease in United States 2019. U.S. Department of Health and Human Services.

Kovesdy, C. P., Furth, S., Zoccali, C., & World Kidney Day Steering Committee. 2017. Obesity and kidney disease: Hidden consequences of the epidemic. Indian journal of nephrology, 27(2), 85–92. https://doi.org/10.4103/ijn.IJN_61_17

Michael E.Hall., Wei Wang., Victoria Okhomina., Mohit Agarwal., John E. Hall., et al. 2016. Cigarette Smoking and Chronic Kidney Idsease in African Americans in the Jackson Heart Study. Journal of the American Heart Association. 2016. Vol 5(6). https://doi.org/10.1161/JAHA.116.003280

Esteban Cedillo dan Ana C. Ricardo. 2016. Smoking, Vascular Events, and ESRD in Patients with CKD. American Journal Kidney Disease. Vol 68(3):338-340. https://doi.org/10.1053/j/akjd.2016.06.004

Zhenliang Fan., Jie Yun., Shanshan Yu., Qiaorui Yang., dan Liqun Song. 2019. Alcohol Consumption Can be a Double-Edged Sword for Chronic Kidney Disease Patients. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research. 2019; Vol 25:7059-7072. https://doi.org/10.12659/MSM.91




DOI: http://dx.doi.org/10.35329/jkesmas.v6i2.1876

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